Toxicological characteristics of a new drug Express Uspokoin® tablets for situational correction of behavioral abnormalities in cats and dogs

Trazodone is a selective antagonist and serotonin reuptake inhibitor used in medicine to treat anxiety. Toxicological studies of trazodone succinate were carried out on the basis Department Pharmacology Veterinary Faculty Stavropol State Agrarian University, Russia.
 The results obtained study acute toxicity drug Express Uspokoin® tablets allow us identify new as belonging moderately dangerous substances for mammals.
 When studying subchronic rats, it was found that its use 90 days at doses 10...50 times higher than therapeutic one does not cause changes clinical condition experimental rats.
 totality data unambiguously confirms good tolerability tablets.
 As result toxicological studies, exhibit irritating allergizing effects.